AustralieFrV1, Main, Exploration, bibRecord, 001314

A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.

Identifieur interne : 001314 ( Main/Exploration ); précédent : 001313; suivant : 001315

A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.

Auteurs : Romal Stewart [Australie] ; Gautam Wali [Australie] ; Chris Perry [Australie] ; Martin F. Lavin [Australie] ; Francois Féron [France] ; Alan Mackay-Sim [Australie] ; Ratneswary Sutharsan [Australie]

Source :

Methods in molecular biology (Clifton, N.J.) [ 1940-6029 ] ; 2017.

RBID : pubmed:28477134

Abstract

The molecular pathogenesis of ataxia-telangiectasia (A-T) is not yet fully understood, and a versatile cellular model is required for in vitro studies. The occurrence of continuous neurogenesis and easy access make the multipotent adult stem cells from the olfactory mucosa within the nasal cavity a potential cellular model. We describe an efficient method to establish neuron-like cells from olfactory mucosa biopsies derived from A-T patients for the purpose of studying the cellular and molecular aspects of this debilitating disease.

DOI: 10.1007/978-1-4939-6955-5_28
PubMed: 28477134

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.</title>
<author><name sortKey="Stewart, Romal" sort="Stewart, Romal" uniqKey="Stewart R" first="Romal" last="Stewart">Romal Stewart</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Queensland Centre for Clinical Research, Brisbane, QLD, 4006, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Queensland Centre for Clinical Research, Brisbane, QLD, 4006</wicri:regionArea>
<wicri:noRegion>4006</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wali, Gautam" sort="Wali, Gautam" uniqKey="Wali G" first="Gautam" last="Wali">Gautam Wali</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111</wicri:regionArea>
<wicri:noRegion>4111</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Perry, Chris" sort="Perry, Chris" uniqKey="Perry C" first="Chris" last="Perry">Chris Perry</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Otolaryngology Head and Neck Surgery, Princess Alexandra Hospital, Woolloongabba, Brisbane, QLD, 4012, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Otolaryngology Head and Neck Surgery, Princess Alexandra Hospital, Woolloongabba, Brisbane, QLD, 4012</wicri:regionArea>
<wicri:noRegion>4012</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lavin, Martin F" sort="Lavin, Martin F" uniqKey="Lavin M" first="Martin F" last="Lavin">Martin F. Lavin</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Queensland Centre for Clinical Research (UQCCR), University of Queensland, Herston, Brisbane, QLD, 4006, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Queensland Centre for Clinical Research (UQCCR), University of Queensland, Herston, Brisbane, QLD, 4006</wicri:regionArea>
<wicri:noRegion>4006</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Feron, Francois" sort="Feron, Francois" uniqKey="Feron F" first="Francois" last="Féron">Francois Féron</name>
<affiliation wicri:level="4"><nlm:affiliation>Aix Marseille Université, CNRS, NICN, UMR7259, 13344, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Université, CNRS, NICN, UMR7259, 13344, Marseille</wicri:regionArea>
<placeName><settlement type="city">Marseille</settlement>
<region type="région" nuts="2">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
<orgName type="university">Université d'Aix-Marseille</orgName>
</affiliation>
</author>
<author><name sortKey="Mackay Sim, Alan" sort="Mackay Sim, Alan" uniqKey="Mackay Sim A" first="Alan" last="Mackay-Sim">Alan Mackay-Sim</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111</wicri:regionArea>
<wicri:noRegion>4111</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sutharsan, Ratneswary" sort="Sutharsan, Ratneswary" uniqKey="Sutharsan R" first="Ratneswary" last="Sutharsan">Ratneswary Sutharsan</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111, Australia. r.sutharsan@griffith.edu.au.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111</wicri:regionArea>
<wicri:noRegion>4111</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:28477134</idno>
<idno type="pmid">28477134</idno>
<idno type="doi">10.1007/978-1-4939-6955-5_28</idno>
<idno type="wicri:Area/PubMed/Corpus">001301</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001301</idno>
<idno type="wicri:Area/PubMed/Curation">001283</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001283</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001283</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001283</idno>
<idno type="wicri:Area/Ncbi/Merge">004765</idno>
<idno type="wicri:Area/Ncbi/Curation">004765</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">004765</idno>
<idno type="wicri:Area/Main/Merge">001309</idno>
<idno type="wicri:Area/Main/Curation">001314</idno>
<idno type="wicri:Area/Main/Exploration">001314</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.</title>
<author><name sortKey="Stewart, Romal" sort="Stewart, Romal" uniqKey="Stewart R" first="Romal" last="Stewart">Romal Stewart</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Queensland Centre for Clinical Research, Brisbane, QLD, 4006, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Queensland Centre for Clinical Research, Brisbane, QLD, 4006</wicri:regionArea>
<wicri:noRegion>4006</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wali, Gautam" sort="Wali, Gautam" uniqKey="Wali G" first="Gautam" last="Wali">Gautam Wali</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111</wicri:regionArea>
<wicri:noRegion>4111</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Perry, Chris" sort="Perry, Chris" uniqKey="Perry C" first="Chris" last="Perry">Chris Perry</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Otolaryngology Head and Neck Surgery, Princess Alexandra Hospital, Woolloongabba, Brisbane, QLD, 4012, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Otolaryngology Head and Neck Surgery, Princess Alexandra Hospital, Woolloongabba, Brisbane, QLD, 4012</wicri:regionArea>
<wicri:noRegion>4012</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lavin, Martin F" sort="Lavin, Martin F" uniqKey="Lavin M" first="Martin F" last="Lavin">Martin F. Lavin</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Queensland Centre for Clinical Research (UQCCR), University of Queensland, Herston, Brisbane, QLD, 4006, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Queensland Centre for Clinical Research (UQCCR), University of Queensland, Herston, Brisbane, QLD, 4006</wicri:regionArea>
<wicri:noRegion>4006</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Feron, Francois" sort="Feron, Francois" uniqKey="Feron F" first="Francois" last="Féron">Francois Féron</name>
<affiliation wicri:level="4"><nlm:affiliation>Aix Marseille Université, CNRS, NICN, UMR7259, 13344, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Université, CNRS, NICN, UMR7259, 13344, Marseille</wicri:regionArea>
<placeName><settlement type="city">Marseille</settlement>
<region type="région" nuts="2">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
<orgName type="university">Université d'Aix-Marseille</orgName>
</affiliation>
</author>
<author><name sortKey="Mackay Sim, Alan" sort="Mackay Sim, Alan" uniqKey="Mackay Sim A" first="Alan" last="Mackay-Sim">Alan Mackay-Sim</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111</wicri:regionArea>
<wicri:noRegion>4111</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sutharsan, Ratneswary" sort="Sutharsan, Ratneswary" uniqKey="Sutharsan R" first="Ratneswary" last="Sutharsan">Ratneswary Sutharsan</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111, Australia. r.sutharsan@griffith.edu.au.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, 4111</wicri:regionArea>
<wicri:noRegion>4111</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Methods in molecular biology (Clifton, N.J.)</title>
<idno type="eISSN">1940-6029</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The molecular pathogenesis of ataxia-telangiectasia (A-T) is not yet fully understood, and a versatile cellular model is required for in vitro studies. The occurrence of continuous neurogenesis and easy access make the multipotent adult stem cells from the olfactory mucosa within the nasal cavity a potential cellular model. We describe an efficient method to establish neuron-like cells from olfactory mucosa biopsies derived from A-T patients for the purpose of studying the cellular and molecular aspects of this debilitating disease.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>France</li>
</country>
<region><li>Provence-Alpes-Côte d'Azur</li>
</region>
<settlement><li>Marseille</li>
</settlement>
<orgName><li>Université d'Aix-Marseille</li>
</orgName>
</list>
<tree><country name="Australie"><noRegion><name sortKey="Stewart, Romal" sort="Stewart, Romal" uniqKey="Stewart R" first="Romal" last="Stewart">Romal Stewart</name>
</noRegion>
<name sortKey="Lavin, Martin F" sort="Lavin, Martin F" uniqKey="Lavin M" first="Martin F" last="Lavin">Martin F. Lavin</name>
<name sortKey="Mackay Sim, Alan" sort="Mackay Sim, Alan" uniqKey="Mackay Sim A" first="Alan" last="Mackay-Sim">Alan Mackay-Sim</name>
<name sortKey="Perry, Chris" sort="Perry, Chris" uniqKey="Perry C" first="Chris" last="Perry">Chris Perry</name>
<name sortKey="Sutharsan, Ratneswary" sort="Sutharsan, Ratneswary" uniqKey="Sutharsan R" first="Ratneswary" last="Sutharsan">Ratneswary Sutharsan</name>
<name sortKey="Wali, Gautam" sort="Wali, Gautam" uniqKey="Wali G" first="Gautam" last="Wali">Gautam Wali</name>
</country>
<country name="France"><region name="Provence-Alpes-Côte d'Azur"><name sortKey="Feron, Francois" sort="Feron, Francois" uniqKey="Feron F" first="Francois" last="Féron">Francois Féron</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001314 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001314 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:28477134
   |texte=   A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:28477134" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.

A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.